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詳細(xì)介紹 Arterolane
產(chǎn)品活性:Arterolane 是一種抗瘧疾劑,對(duì) P. falciparum Ro73 和 W2 的 IC50 值均為 1.1 nM。
研究領(lǐng)域:Anti-infection
作用靶點(diǎn):Parasite
In Vitro: Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively.
相關(guān)產(chǎn)品:FDA-Approved Drug Library Plus | Drug Repurposing Compound Library | Anti-Infection Compound Library | FDA-Approved Drug Library | Drug Repurposing Compound Library Plus | Bioactive Compound Library Plus | Hydroxychloroquine sulfate | Emetine dihydrochloride hydrate | Metronidazole | Dihydroartemisinin | Artemisinin | Fluralaner | Ivermectin | Levamisole hydrochloride | RRx-001 | Avermectin B1 | Quinidine | Pyrimethamine | Artemether | Bithionol | Mefloquine hydrochloride | SQ109 | Flubendazole | Mebendazole | Atovaquone | DSM265 | Hycanthone | Proguanil | Albendazole | Cipargamin | Methoprene | Paromomycin sulfate | Closantel | Fexinidazole | Quinine | Fenbendazole
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