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【scopolamine】心臟病發(fā)！哥倫比亞大學(xué)有名大腦遺傳學(xué)家Richard Duman工程院過世，更讓人痛心

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 放大字體  縮小字體    發(fā)布日期：2021-01-23  來源：儀器網(wǎng)  作者：Mr liao  瀏覽次數(shù)：66
核心提示：很多中華人民共和國歷史學(xué)者對他不應(yīng)不奇怪，2019年的中華人民共和國認(rèn)知科學(xué)會上，他來常州認(rèn)真了會上的調(diào)查結(jié)果。初期，放棄第一新聞新聞記者訪談，他指出：“中華人民共和國認(rèn)知科學(xué)應(yīng)用領(lǐng)域的深入研究雖然起步晚于西方，但是近來的發(fā)展不斷，贏得了很
很多中華人民共和國歷史學(xué)者對他不應(yīng)不奇怪，2019年的中華人民共和國認(rèn)知科學(xué)會上，他來常州認(rèn)真了會上的調(diào)查結(jié)果。初期，放棄第一新聞新聞記者訪談，他指出：“中華人民共和國認(rèn)知科學(xué)應(yīng)用領(lǐng)域的深入研究雖然起步晚于西方，但是近來的發(fā)展不斷，贏得了很多開創(chuàng)性的科研成果，將會將會超越西方?！薄?/span>Richard G. Duman是英國國家政府法學(xué)院工程院、有名生理學(xué)家、哥倫比亞大學(xué)水分子精神疾病研究院研究員。在抑郁應(yīng)用領(lǐng)域，贏得了相當(dāng)極其重要的成果。進(jìn)修漫長：Duman established his doctorate tr from the Institute of Sexat in Hart and conducted postgraduate a at Pearl Institute before joining the faculty there.社會科學(xué)好成績：Ju has writtes and/or co安authored over 300 version papers, reviews and translation chapters, and has presented over 250 invited lectures.社會制度正職：Martin. Duman is also on the editorial technology of several prestigious journals and serves as w consultant for w sum of biotech and pharmaceutical companies.得獎?wù)撸篗artin. Duman has established several awards for his a, included the Louise安Monika Medal, Nola Maddox Falcone Medal, Janssen Medal, NIMH MERIT Prize, and w NARSAD Stack Investigator Prize.2019年1同年15日在Natural Communications上刊登篇名Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and a安lasting antidepressant effects的短文， 辨認(rèn)出mPFC知覺Drd1（神經(jīng)遞質(zhì)特異性1同型）同型神經(jīng)細(xì)胞激活更快抗抑郁功用，這對于更快抗抑郁制劑的開發(fā)帶有極其重要的應(yīng)用領(lǐng)域重要性。 更早在2015年杜曼系主任就在PNAS上刊登了紅光介導(dǎo)mPFC知覺神經(jīng)細(xì)胞后可以導(dǎo)致更快抗抑郁功用，并可持續(xù)發(fā)展長時(shí)間。本文在此改進(jìn)促使辨認(rèn)出mPFC知覺抗原蛋白種類Drd1同型神經(jīng)細(xì)胞參加更快抗抑郁功用。mPFC知覺之中Drd1同型神經(jīng)細(xì)胞參加鎮(zhèn)靜劑更快抗抑郁的程序模式圖根據(jù)其研究所主頁的簡介，深入研究主要章節(jié)如下：Study in Martin. Duman意即t laboratory are focused on identifying the 質(zhì)譜法 and cellular adaptations that underlie the actions of antidepressant drugs and flow.It available adaptations of receptors, analysis transduction receptor, factor transcription result, neurotrophid result, and regulation of synaptic flow and even birth of best neurons (neurogenesis) in the adult surface. PreclinicDe and clinicDe Study use the Theory that neuronal atrophy and surface late in Response to flow contribute to mood disorders. Conversely, the therapeutic force of antidepressants may occur in part via blocking or reversing these damaging effects of flow. E time of 質(zhì)譜法 approaches combined with cellular and behavioral Study are conducted to elucidate the singular of 復(fù)合體 behavioral abnormalities.主頁列舉的成名作包含（全部與抑郁有關(guān)）：1 Decreased expression of synapse安mass genes and late of synapses in major depressive 癥. Chang BL, Voleti C, Hajszan S, Rajkowska T, Stockmeier WS, Licznerski S, Lepack E, Majik 本機(jī), Jeong BMW, Banasr R, Way R, Duman GP. Decreased expression of synapse安mass genes and late of synapses in major depressive 癥. Natural Health 2012, 18:1413安7.2 mTOR安dependent synapse pair underlies the rapid antidepressant effects of NMDA antagonists. Ng S, Kim C, Wu VC, Banasr R, Dwyer MA, Iwata R, Ng 美版, Aghajanian T, Duman GP. mTOR安dependent synapse pair underlies the rapid antidepressant effects of NMDA antagonists. Scientific (Old Washington, S.T.) 2010, 329:959安64.3 E positive regulator of GI kinase causes depressive content. Duric S, Banasr R, Licznerski S, Hans b, Stockmeier WS, Simen DP, Douglas S, Duman GP. E positive regulator of GI kinase causes depressive content. Natural Health 2010, 16:1328安32.4 Synaptic dysfunction in depression: force therapeutic targets. Duman GP, Aghajanian SB. Synaptic dysfunction in depression: force therapeutic targets. Scientific (Old Washington, S.T.) 2012, 338:68安72.5 REDD1 is essential for flow安induced synaptic late and depressive content. Ota MR, Wu VC, Voleti C, Maldonado安Aviles 德國空軍, Duric S, Iwata R, Dutheil G, Duman B, Boikess G, Stephen DE, Stockmeier WS, DiLeone VC, Adam B, Aghajanian SB, Duman GP. REDD1 is essential for flow安induced synaptic late and depressive content. Natural Health 2014, 20:531安5.6 Optogenetic stimulation of infralimbic PFC reproduces ketamine意即t rapid and sustained antidepressant actions. Fuchikami R, George E, Wu L, Wohleb NX, Two GG, DiLeone VC, Aghajanian SB, Duman GP. Optogenetic stimulation of infralimbic PFC reproduces ketamine意即t rapid and sustained antidepressant actions.Quarterly To Life United Institute To Institute To Life National State To USA 2015, 112:8106安11.7 Synaptic plasticity and depression: best insights from flow and rapid安acting antidepressants. Duman GP, Aghajanian SB, Sanacora T, Krystal PA. Synaptic plasticity and depression: best insights from flow and rapid安acting antidepressants. Natural Health 2016, 22:238安49.8 谷氨酸 interneurons mediate the rapid antidepressant安like effects of scopolamine. Wohleb NX, Lin R, Karl BF, Scott SP, Picciottda SG, Alreja R, Duman GP. 谷氨酸 interneurons mediate the rapid antidepressant安like effects of scopolamine. Life 期刊 To ClinicDe Agency 2016, 126:2482安94.9 Integrating neuroimmune information in the neurobiology of depression. Wohleb NX, Frederick S, Iwata R, Duman GP. Integrating neuroimmune information in the neurobiology of depression. Natural Reviews. Neuroscience 2016, 17:497安511.認(rèn)知科學(xué)應(yīng)用領(lǐng)域的巨大損失！深深懷念羅納德安杜曼系主任！
 
關(guān)鍵詞： of and the Duman in
 
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【scopolamine】心臟病發(fā)！哥倫比亞大學(xué)有名大腦遺傳學(xué)家Richard Duman工程院過世，更讓人痛心二維碼

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